5234
Dina Mahfouz Eskander
Phytochemical and Bioactivity Studies on Ipomoea cairica (L.) Sweet and Jacquemontia pentantha (Jacq.) G. Don (Family Convolvulaceae)
Jacquemontia pentantha - Ipomoea cairica - Convolvulaceae - DNA fingerprinting - proximate analysis – flavonoids – quantitative phenolic acids - HPLC profile - biological activities ).
This work includes phytochemical and bioactivity studies on Jacquemontia pentantha (Jacq.) G Don and Ipomoea cairica (L.) Sweet, family Convolvulaceae. Studying the following: literature survey of phytoconstituents and bioactivities of certain Convolvulaceae species, DNA fingerprinting, phytochemical screening and proximate analysis of both plants, HPLC profile of flavonoid compounds of both plants, quantitative estimation of phenolic acids and flavonoids of the aerial parts of both plants and isolation, characterization and structure elucidation of the main constituents in the methanol soluble fraction of the aerial parts of Jacquemontia pentantha (Jacq.) G. Don .Also, evaluation of certain biological activities of extracts of the aerial parts of both plants including: determination of acute toxicity (LD50), anti-inflammatory activity, antihyperglycemic activity, antioxidant activity and hepatoprotective activity and also evaluation of antimicrobial activity of extracts of the aerial parts of both plants .
2016
Ph.d
Cairo
Pharmacy