5058
AHMED ELSAYED MOHAMED ELSAYED KAID
SEROPREVALENCE OF ANTIBODIES AGAINST HIGTTLY PAir{ocnNrc AvIAN TNFLUENzA VIRUSES AINTOXG EGYPTIAN FARMERS nxposnu TO POULTRY
Influenza, Avian, Epidemioiogy, Seroprevalence, Mi croneut r aliz ation as s aY.
Avian influenza virus H5N1 causes mass loss in poultry production in Egypt since 2006. The first confirmed human case in Egypt was detected in Vfarctr 2006 in Qaliyoubia governorate for 30 years old woman. Avian influenza virus H5N1 raises serious public health concern because of its potential to spread to humans and causes a global pandemic. Clade 2'2 of tfSNt avian influenza viruses ale enzootic in Egyptian poultry and are responsible for the majority of confirmed human cases since 2009, which rise "oo..* for Egypt in threat of zoonotic disease of influenza, especially with shortness in real number of human cases, and subclinical cases. This study was performed to assess the risk factor, and to identify the prevalence of influinza virus among Egyptian farmers. Seven hundred and fifty poultryexposed subjects were effo|led in 5 rural governorates (Sharkiya, Gharbiya, Fayoum, Qaiyubiya, and Kafr El Sheikh) and250 unexposed control subjects in Cairo. ,Lriorg the exposed individuals, the seroprevalence of anti-H5Nl antibodies at baseline was 2.lYo, while for the unexposed individuals, the prevalence was 0ol0. Results indicated that the numbers of humans infected with avian influenza viruses were much higher than those reported officially as confirmed cases. Also, when influenza viruses are enzootic in the poultry in a speciftc area, this led to hdman exposure and infection with avianinfluenza virusqi
2015
M.Sc
Cairo
Agriculture