5685
Fatma Alzahraah Mostafa Gomah
Left Ventricular Dysfunction by "Conventional" and
"Tissue Doppler" Echocardiography in Pediatric
Hemodialysis Patients: Relation with Plasma Brain
Natriuretic Peptide Levels
chronic cideney disease in pedialric age group, tissue doppla imaging conrcntional echo cardio graphy , ttemodialysis
Left ventricular systolic and diastolic dysfunction contribute to high cardiovascular mortality in chronic kidney disease patients. Aim: To evaluate LV diastolic function in children with ESRD using cPWD and TDI, and to compare the findings with BNP. Methods: This study was designed as a prospective cohort investigation in which BNP concentrations were measured and echocardiographic parameters were obtained 30 min before and 30 min after HD in consecutive ESRD children. The study protocol was approved by the Ethics Committee of our institution, and written informed parental consent was obtained from the parents of each patient before the study. Parameters related to LV systolic and diastolic function were compared in the ESRD patients and control groups. Result: LV. diastolic dysfunction is common. In paediatric dialysis. Patients and TDI can be used to unmask the presence of subclinical diastolic dysfunction in asymptomatic ESRD patients with higher frequency than cPW Doppler. Care. Should be taken in interpreting BNP .levels because children with ESRD. May show a high concentration of BNP. Independent of heart dysfunction. in volumeoverloaded patients.
2020
Ph.d
Cairo
Medicine