5518
Heba Nader Morsy Shalash
The Effect Of Salivary Gland-Derived Stem Cell Transplantation On The Regeneration Of Gamma-Irradiated Rat Submandibular Salivary Glands (An Ex-Vivo And In-Vivo Study)
Salivary Gland, Stem Cell Transplantation , Gamma-Irradiated
Salivary glands are responsible for maintaining the health of the oral cavity and are routinely damaged by therapeutic radiation for head and neck cancer as well as by autoimmune diseases such as Sjogren’s syndrome. Regenerative approaches based on the reactivation of endogenous stem cells or the transplant of exogenous stem cells hold substantial promise in restoring the structure and function of these organs to improve patient quality of life. However, these approaches have been hampered by a lack of knowledge on the identity of salivary stem cell populations and their regulators. Recently, tissue-specific stem cell therapy has attracted public attention as a next-generation therapeutic reagent.
2018
Ph.d
Ain Shams
Dental Medicine