5099
Tarek Nour Soliman Ismail
THE USE OF WHEY PROTEIN HYDROGEL AS POTENTIAL ENCAPSULATION MATRIX FOR THE DELIVERY OF BIOACTIVE COMPOUNDS
Whey protein isolate, Hydrogel, Microparticles, Nanoparticles, Curcumin, selenite, Functional yogurt.
Many natural bioactive compounds bear various health-promoting benefits and can be incorporated in functional foods. The utilization or the bioavailability of the compounds in human body is usually not taken into consideration in the process of food formulation. In this Ph.D. study, the effect of pH on hydrogel formation and the problems of the poor bioavailability of polyphenols, such as curcumin, and Selenium (Se) which has been recognized as an essential nutrient limits their utilization. In addition at high concentration selenium can become toxic. The difference between the concentration in which selenium can be essential or toxic element at is very narrow. The two problems have been addressed by complexion with delivery systems micro and nanoscale.The effects of pH and added curcumin and selenium of the textural properties and microstructure of whey protein isolate (WPI) gels were investigated. WPI gels were prepared at pH 4-9, without and with the addition of one mg curcumin or one mg selenium / g protein respectively. The texture profile (TPA), and viscoelastic properties of the prepared gels were determined, and the gels microstructures were examined by scanning electron microscopy. All TPA parameters and viscoelastic measurements were affected significantly by changing pH. Gels prepared at pH 5 were characterized by harder texture than that prepared at higher or lower pH values. Addition of curcumin (CCM) or selenium (Se) had no significant effects on TPA or viscoelastic measurements of the gels. Gels prepared at pH 4 -6 were characterized by coarser microstructure than those prepared at higher pH values. Apparent changes in the gel microstructure occurred on addition of curcumin and selenium at pH 4-6 being less coarser than WPI gels without their additions.
2016
Ph.d
Ain Shams
Agriculture