5029
Maysa Samir Mahmoud Nassar
Changes In Adipocyte Hormones In Relation To Body Composition And Pubertal Development In Obese Adolescents After Physical Activity And Dietary- Restriction Programs
Obesity, Adiponectin and Leptin hormones, physical activity, diet restriction.
Background: The prevalence of obesity continues to rise in both developed and developing nations. An association has been reported between plasma level of adiponectin and leptin hormones and the existence of adolescent obesity. Findings from recent reports suggest that intervention with structured exercise and diet program support to modulation of the level of these hormones and also the BMI. Aim of the study: The aim of this study was to investigate the changes in Adipocyte hormones in relation to body composition and pubertal development in obese adolescents after physical activity and dietary restriction program. Subjects and Methods: the present study was conducted on 60 adolescents aging 12-14 years old, divided into two groups. Group (A): adolescents presenting with obesity and who were subjected to exercise and diet program. Group (B): adolescents presenting with obesity and who were subjected to diet program only. Both groups (A&B) were subjected to the following before and after 6 months of the program: full medical history taking, anthropometric measurements, thorough clinical examination, body composition analysis, laboratory investigations: lipid profile and hormonalassessment. Results: Both groups (A&B) showed significantly elevation of the levels of adiponectin hormone, significant reduction in level of leptin hormone, BMI, WC, WHR, TG, Cholesterol ,LDL, SBP, DBP, FAT %,VF. No significant difference was found between both groups except in fat% after the program, there was significant reduction in group A than that of group B. Plasma adiponectin level correlated positively with cholesterol in group A after the intervention program but leptin correlated negatively with BMI ,DBP and adiponectin in group A after the intervention program . Conclusion: Results of the present study reported that the plasma level of Adiponectin hormone will increase and the plasma level of Leptin hormone will decrease through physical activity and diet programs intervention in obese adolescent
2015
Ph.d
Ain Shams
Medicine