5630
Hoda Sabry Othman Ahmed
Chemically Modified Precursors Driven From Wastes With Anticipated Industrial Applications
Biomass, Sustainability, Lignin, Nitrile Butadiene Rubber, Electrical conductivity, Copper composites, Antimicrobial, Antioxidant, Pyrimidine, Cyanoacetyl urea, Bioactive small molecules.
This study represents an example of the optimal utilization of biomass wastes instead of being disposed via improper and environmental-hazardous ways. In the first chapter after the literature review, a series of α,β unsaturated ketones having acylic sugar residue was synthesized along with their hydrazone analogues and investigated by spectral analysis. In addition, the newly synthesized compounds were tested and evaluated as antimicrobial and antioxidant agents. Results revealed that compound 2d is the most promising antimicrobial agent among the tested compounds and it even exceeds the activity of the used standard antibacterial drug Ampicillin as well as it competes with the standard antifungal drug Amphotericin B, while compound 3b shows potent antioxidant activity in comparison with the used standard drug Trolox. Structure-activity relationship is also discussed.
2020
Ph.d
Ain Shams
Science